-Vircow's triad.

Vircow's triad is the aetiology of thrombosis which is composed of :-

1-Damage of vascular endothelium(Vascular trauma):-
this damage expose the endothelial collagen which is rough surface to which platelets can stick firmly and release thromboxane A2 that help more platelet aggregation.

2-Slowing(Reduced)in the blood flow (stasis):-
these changes help thrombosis by allowing the platelets to deviate from the axial stream and cross the peripheral plasmatic zone to stick to the vascular endothelium.

3-Change in blood composition(Increased coagulability ):-
a-Increase number of blood elements.
-Increase platelets so become more sticky and agglutinate in small masses and adhere to vascular endothelium.
-Increase WBCs and RBCs increase viscosity of blood and stasis.
b-Biochemical changes that cause systemic activation of the cloting system.

"VIR chow"

Vascular trauma
Increased coagulability
Reduced blood flow (stasis)

Dr Ibrahim

Return to other triads here.

- Medical syndromes.

Medical syndrome is defined as :-
A group of symptoms and signs that collectively indicate or characterize a disease, psychological disorder, or other abnormal condition.
There are a lot of medical syndromes and we try to list some of them:-
1-Down syndrome (click here).
2-Plummer-Vinson syndrome (click here).
3-Ramsay Hunt syndrome (click here).
4-Wolf-Hirschhorn Syndrome (click here).
5-Cri-du-chat syndrome (click here).
6-YY syndrome (click here).
7-Klinefelter's syndrome (click here).
8-Turner's syndrome (click here).
9- Fanconi syndrome (click here).
10-Abderhalden-Kaufmann-Lignac syndrome (click here) .
11-Light Wood-Albright syndrome(Lightwood syndrome)(click here).
12-Oculo-cerebro-renal Syndrome (click here).
13-Metabolic syndrome (click here).
14-Pickwickian syndrome (click here).
15- Kallmann syndrome (click here).
16-Sertoli-cell-only syndrome (click here).
17-Lambert-Eaton syndrome (click here).
18-Guillain Barré syndrome (click here).
19-Horner's syndrome (click here).
20-Brown-Séquard syndrome. (click here).
21-Carpal tunnel syndrome. (click here).
22-Sjögren's syndrome (click here).
23-Felty's syndrome (click here).
24-Caplan's syndrome (click here).
25-Congenital Rubella Syndrome  (click here).
26-Caroli's syndrome.  (click here).
27-Malabsorption syndrome.  (click here).
28-Duhin-Johnson syndrome.  (click here).
29-Exploding head syndrome. (click here). 

If you have other syndromes plz tell us...
Dr Ibrahim,,

-Dangerous area of the face.

Dangerous area of the face

- It is the area () the root of  the nose and 2 angles of the mouth.
- The veins in this region are connected to cavernous sinus so any infection in this area may lead to cavernous sinus thrombosis.

- Venous draingae of Dangerous area:-

• Antearior and  post etmoidal veins drain to opthalmic vein.
• sphenopalatine & greater palatine veins drain to pterygoid veins.
• Angular vein,lateral nasal and superior labial veins drain to facial vein...

- All of the above veins drain finally to cavernous sinus.

So, Donnot put your finger in your nose..:)

See you,
Dr Ibrahim...

- pathology mnemonics (1)

Thrombus: possible fates

DOPE:-

• Dissolution
• Organization and repair
• Propagation
• Embolization

Atherosclerosis risk factors

SAD BET (الرهان الحزين)

Sex: male
Age: middle-aged, elderly
Diabetes mellitus

BP high: hypertension
Elevated cholesterol(bad cholesterol LDL)
Tobacco (smoking)

Dr Ibrahim

- Intussusception of the intestine.

Intussusception of the intestine

Def: Invagination of proximal segment of the intestine into distal one.

According to the direction of the intestinal wave from proximal to distal.

-The proximal part  is called the intussusceptum.
-The distal part that receives it is called the intussuscipiens.
 

see you,

Dr Ibrahim.

-Shape of infarction.

- usually All infarcts tend to be pyramidal or wedge shaped.

- Why?

Due to distribute of the branches of arteries which

distribute in an area of pyramid

so when the infarction occur the base

become at the surface & apex become at the site

of occluded artery,see the figure...

see you,

Dr Ibrahim.