Sunday, December 13, 2009

- Light Wood-Albright syndrome.

Light Wood-Albright syndrome
Lightwood syndrome
Renal tubular acidosis (RTA) (Type-2)
(Proximal RTA)


it is caused by failure of the proximal tubular cells to reabsorb filtered bicarbonate from the urine, leading to urinary bicarbonate wasting and subsequent metabolic acidosis.

-Clinical picture:-

  • Rickets(in children).
  • Osteomalacia (in adults).
  • Metabolic acidosis.
  • Vomiting ( due to acidosis).
  • Polyuria and polydepsia.
  • Episodes of fever and dehydration.
  • Muscle weakness and constipation.
  • Growth retardation.
  • Ph (decrease).
  • Ca++ (Normal).
  • Alkaline phosphatase (increased).
  • increase urinary phosphate,bicarbonate,glucose, amino acids and may be Potassium.
  • Oral phosphate 1-3 gm/day divided into 5 doses.
  • Vitamin D: 2000 IU/day.
  • Sodium bicarbonate tablets or Sodium citrate and Potassium citrate syrup for metabolic acidosis.
  • Potassium chloride 2-3 mEq/kg/day for cases of hypokalemia.

Return to list of medical syndromes here

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