-Caroli's syndrome.

Caroli's syndrome.

Def:-
It is a congenital segmental dilatation of the intrahepatic biliary system.

Clinical picture:-

• Recurrent attacks of cholangitis.
• liver abscesses may occur.

Complications:-

• Biliary stones.
• Cholangiocarcinoma.

Treatment:-

• Antibiotics for cholangitis.
• Segmental liver resection for localized disease.

Dr Ibrahim

Return to list of medical syndromes here

-Iatrogenic endocrinal diseases.

Iatrogenic endocrinal diseases
"TV as Milk"

Thyroxin therapy lead to thyrotoxicosis.
Vit D lead to hypercalcaemia.

Amiodarone lead to thyroid dysfunction.
ACEIs lead to hypoaldosteronism.
Sympathomimetics lead to picture like thyrotoxicosis.
Steroid therapy lead to DM and cushing syndrome.

Metoclopramide lead to hyperprolactinaemia.
Iodide lead to hyperthyrodism.
Insulin and oral hypoglycemic lead to hypoglycemia.
Lithium lead to hypothyrodism.
Ketoconazole lead to hypoadrenalism.

Dr Ibrahim

-Psychic features of Hyperthyrodism.

Psychic features of Hyperthyrodism.

"Mania"

• Mental disturbance.
• Anxiety.
• Nervousness.
• Insomnia.
• Agitation.
   

Dr Ibrahim

-Congenital Rubella Syndrome.

Congenital Rubella Syndrome

Aetiology:-
Maternal infection by rubella leads to Maternal viremia which lead to transplacental spread of the virus to the fetus causing fetal viremia whcih in turn leads to infection invloving many fetal organs and hence congenital anomalies.

N.B:- Newborn discharge virus in his secretions for 12-18 months after birth so he is infectious.
Incidence:-
*In the 1st trimester:- 15-20%.
*In the 4th month:- 5%.