- ACR Criteria for Diagnosis of SLE.

American college of Rheumatology (ACR) Criteria

for Diagnosis of Systemic Lupus Erythematosus.

"Sharp Domain"

1. Serositis:Pleuritis, pericarditis.
2. Hematologic disorder (hemolytic anemia OR Leukopenia less than 4,000 OR Lymphopenia less than 1500 or thrombocytopenia less than 100,000).
3. Arthritis:-(nonerosive, involving 2 or more joints).
4. Renal disorder:-(persistent proteinuria > 0.5 grams per day OR cellular CASTS).
5. Photosensitivity:- Rash on exposure to sun light.
   
    
   
6. Discoid rash.
7. Oral ulcers:(oral or nasopharyngeal).
8. Malar rash.
9. Anti-nuclear antibody (+ve).
10. Immunologic disorder:Anti-dsDNA,anti-Smith antibody ,false positive VDRL or + ve L.E cells.
11. Neurologic disorder (seizures OR psychosis).

Any combination of 4 or more of 11 criteria, well-documented at any time during a patient's history is essential to diagnose SLE.

Dr Ibrahim