Wednesday, April 14, 2010

- ACR Criteria for Diagnosis of SLE.

American college of Rheumatology (ACR) Criteria
for Diagnosis of Systemic Lupus Erythematosus.

"Sharp Domain"
  1. Serositis:Pleuritis, pericarditis.
  2. Hematologic disorder (hemolytic anemia OR Leukopenia less than 4,000 OR Lymphopenia less than 1500 or thrombocytopenia less than 100,000).
  3. Arthritis:-(nonerosive, involving 2 or more joints).
  4. Renal disorder:-(persistent proteinuria > 0.5 grams per day OR cellular CASTS).
  5. Photosensitivity:- Rash on exposure to sun light.

  6. Discoid rash.
  7. Oral ulcers:(oral or nasopharyngeal).
  8. Malar rash.
  9. Anti-nuclear antibody (+ve).
  10. Immunologic disorder:Anti-dsDNA,anti-Smith antibody ,false positive VDRL or + ve L.E cells.
  11. Neurologic disorder (seizures OR psychosis).

Any combination of 4 or more of 11 criteria, well-documented at any time during a patient's history is essential to diagnose SLE.

Dr Ibrahim

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