- Side effects of antithyroid drugs.

Side effects of antithyroid drugs.

"Charge"

Cholestatic jaundice.
Hypothyroidism.
Allergy,Agranulocytosis.
Relapse on sudden stoppage.
Goiter,Git upsets.
Exophthalmos increase.

enjoy,,

Dr Ibrahim

-Duhin-Johnson syndrome.

Duhin-Johnson syndrome.

It is Autosomal recessive disease characterized by Partial defect in excretion of conjugated bilirubin into the bile.

*Clinical picture:-It is usually asymptomatic.

1. Jaundice.
2. Good general condition.

*Investigations:-

1. Bilirubin: mild elevation of direct bilirubin
2. Biopsy (dark pigment inside hepatocytes i.e the liver is black in colour), it had been proved to be a metabolite of catecholamines.
3. +ve Bromosulphthalein (BSP) Test: Normally 90% of this dye is removed from blood within 45 minutes after I.V injection in normal liver.
In Dubin-Johnson syndrome there is a late rise in plasma SSP after an initial fall due to reflux of the dye from the liver reflecting hepatic excretion defect.
4. No evidence of obstruction.
5. No evidence of LCF.

*Treatment:-

No treatment (almost normal life span).

Dr Ibrahim

Return to list of medical syndromes here

-Local Complications of pneumonia.

Local Complications of pneumonia
"Idea"

Incomplete resolution and followed by bronchiectasis later on.
Delayed resolution.
Pleural Effusion,Empyema.
Lung Abscess,ARDS and respiratory failure.

Dr Ibrahim

- Wagner Grading System for Diabetic Foot Infections.

Wagner Grading System for Diabetic Foot Infections

• Grade 0 :- Intact Skin,but high risky foot.
• Grade 1 :- Superficial ulcer of skin or subcutaneous tissue.
• Grade 2 :- Deep Ulcers but no abscess nor bone involvement.
• Grade 3 :- Deep ulcer with osteomyelitis, or abscess.
• Grade 4 : -Gangrene of toes,heel or forefoot (localized).
• Grade 5 :- Gangrene of whole foot.

 Dr Ibrahim
Return to list of medical grades (click here)